In The absence of the enzyme, as in Crigler-Najjar syndrome type I, the levels of unconjugated bilirubin will increase, resulting in jaundice. Unconjugated bilirubin is water-insoluble, and higher amounts can deposit in the Mind leading to a condition called kernicterus. Severe hyperbilirubinemia commonly develops in the main several times of https://www.youtube.com/shorts/IuPMi7CvqAo