Summary: Selective recruitment of protein kinases to the Hsp90 system is mediated by the adaptor co-chaperone Cdc37. We show that assembly of CDK4 and CDK6 into protein complexes is differentially regulated by the Cdc37-Hsp90 system. Like other Hsp90 kinase clients. binding of CDK4/6 to Cdc37 is blocked by ATP-competitive inhibitors. https://yeswellneses.shop/product-category/legumes/
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