Biogenesis of mitochondrial cytochrome c oxidase (COX) is a complex process involving the coordinate expression and assembly of numerous subunits (SU) of dual genetic origin. Moreover. several auxiliary factors are required to recruit and insert the redox-active metal compounds. which in most cases are buried in their protein scaffold deep inside the membrane. https://www.roneverhart.com/2003-2005-HONDA-ACCORD-2-4L-4-Cylinder-Engine-Upper-Intake-Manifold-OEM/
Cytochrome c Oxidase Biogenesis and Metallochaperone Interactions: Steps in the Assembly Pathway of a Bacterial Complex.
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