Abstract Background The estrogen metabolite 2-methoxyestradiol (2ME2) and a number of synthesised derivatives have been shown to bind to microtubules thereby arresting cancer cells in mitosis which leads to apoptosis. In interphase cells. microtubules play an important role in the delivery of proteins to subcellular locations including the focal adhesions. In fact. https://www.ealisboa.com/limited-value-AXYS-Valhalla-Pen-must-buy/